The main ingredient of Nolpaza 20mg is Pantoprazole 20mg. Pantoprazole is a proton pump inhibitor, which inhibits the stomach from secreting basic acid, and when any stimulant stimulates the stomach. So, what are the uses of Nolpaza 20mg?
1. Indications of Nolpaza 20mg
Nolpaza 20mg is indicated for treating stomach pain, stomach ulcers, esophagitis, and some syndromes that cause discomfort in the digestive tract. Specifically:
Used in combination with antibiotics in the treatment of stomach pain caused by Helicobacter pylori
Gastric ulcers, duodenal ulcers
Gastroesophageal reflux
Zollinger - Ellison syndrome
Other conditions of increased acid secretion.
Nolpaza 20mg is contraindicated in patients with hypersensitivity to pantoprazole or any ingredient of the medication or other benzimidazole derivatives.
2. How to use Nolpaza 20mg
Nolpaza 20mg cena should be taken 30 minutes before meals in the morning by swallowing the whole tablet; do not crush, break, or chew. For each disease, the doctor will prescribe the medication in different doses:
- Gastroesophageal reflux syndrome: Usual dose: 20-40 mg x 1 time/day for 4 weeks, can be extended to 8 weeks. Maintenance dose: 20-40 mg per day. In case of recurrence: 20 mg/day.
- Gastrointestinal ulcers: Usual dose: 40 mg x 1 time/day.
- Treatment of Helicobacter pylori: Use a 1-week triple combination therapy regimen: Pantoprazole 40 mg x 2 times/day combined with clarithromycin 500 mg x 2times/day, amoxicillin 1 g x 2 times/day or metronidazole 400 mg x 2 times/day.
- Prevention of gastrointestinal ulcers caused by non-steroidal anti-inflammatory drugs (NSAIDs): 20 mg/day.
- Zollinger - Ellison syndrome: Starting dose: 80 mg/day. You can use doses up to 240 mg/day. If you use more than 80 mg/day, it should be divided into 2 times.
3. Side effects of Nolpaza 20mg
Some common side effects of Nolpaza 20mg include: fatigue, headache, rash, hives, muscle pain, joint pain... Rare side effects include weakness, dizziness, vertigo, itching, increased liver enzymes.
4. Precautions when using Nolpaza 20mg
To use the medication safely, patients need to note the following:
- Using proton pump inhibitors, especially when used in high doses and for a long time, can slightly increase the risk of hip, wrist, and spine fractures, mainly in the elderly or people with other risk factors. Studies show that proton pump inhibitors increase the risk of fractures by 10 to 40%.
- Patients at risk of osteoporosis should be monitored and have adequate vitamin D and calcium supplementation.
- There have been reports of severe hypomagnesemia in patients treated with proton pump inhibitors for at least 3 months and, in most cases, for about 1 year. Symptoms of severe hypomagnesemia include fatigue, muscle cramps, delirium, seizures, dizziness, and ventricular arrhythmias, but these symptoms may occur insidiously. In most patients with hypomagnesemia, improvement occurs after magnesium supplementation and discontinuation of the medication. Serum magnesium levels should be measured before and during treatment in patients requiring long-term treatment or taking proton pump inhibitors concomitantly with digoxin or medications that cause hypomagnesemia (e.g: diuretics).
- Malignant peptic ulceration should be excluded before administering pantoprazole, as it may mask symptoms.
- Mild and transient serum ALT (SGPT) elevations have been reported with oral pantoprazole.
- Pantoprazole may cause cyanocobalamin malabsorption, which may be due to hypochlorhydria or achlorhydria associated with long-term acid-suppressive therapy.
- The safety and efficacy of pantoprazole in children under 18 years of age have not been established.
- Pregnancy: There are no adequate and well-controlled studies of pantoprazole in pregnant women. Only use when needed.
- Breastfeeding women: pantoprazole can be excreted in breast milk, so stop breastfeeding or stop using the medication in this subject.
Some side effects of the medication include dizziness and visual disturbances. Be careful when using the medication for people operating machinery and driving.
To arrange an appointment, please call HOTLINE or make your reservation directly HERE. You may also download the MyVinmec app to schedule appointments faster and manage your reservations more conveniently.
