Acetylcysteine – be careful with people with asthma

This is an automatically translated article.

Acetylcysteine is a medicine used quite commonly to treat cough with phlegm and is easily purchased without a prescription in pharmacies with many different brand names, many different forms of use suitable for other subjects. together. However, the drug also has special precautions when used.

1.Side effects when using Acetylcysteine

In addition to the common undesirable effects with an incidence of > 1%, which are nausea, vomiting, facial flushing, edema, and tachycardia, Acetylcysteine also has a rare but notable side effect, anaphylaxis. and bronchospasm, causing difficulty breathing, respiratory failure. Usually, Acetylcysteine has the effect of dissolving mucus, reducing the viscosity of sputum in purulent lungs, separating disulfide bridges in mucoproteins (components of sputum), making it convenient to expel sputum out by coughing, leading save posture or mechanical method. Acetylcysteine is also known to cause bronchospasm, possibly due to local release of histamine (which is an allergen, anaphylactic reaction).

2.Acetylcysteine should be avoided for asthma patients

Acetylcysteine long đờm — Thuốc acetylcystein

Acetylcysteine should be avoided for people with asthma, although not absolutely contraindicated for this subject. Asthma is also a risk factor and requires special monitoring, including careful assessment of benefits and risks, close monitoring, and availability of emergency facilities and medical personnel to timely treatment when there is a life-threatening bronchospasm.
Therefore, before taking acetylcysteine, it should be noted for people with asthma:
Inform your doctor or pharmacist about your medical history so that you can consider the use of the drug as well as be closely monitored if using the drug. . Do not arbitrarily use without the opinion of medical staff cough and expectorant medicines if you do not know the ingredients of the medicine. If you see any unusual symptoms when using the drug, such as: increased secretion of sputum, mucus (nasal drip, sputum...), hoarseness, difficulty breathing... please come or call a medical facility immediately for help. timely handling. To register for an examination at Vinmec International General Hospital, you can contact the nationwide Vinmec Health System Hotline, or register online HERE.
Source: Vietnam National Pharmacopoeia 2015, Medicines.org.uk, Emergency Medidicine Journal.

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This article is written for readers from Sài Gòn, Hà Nội, Hồ Chí Minh, Phú Quốc, Nha Trang, Hạ Long, Hải Phòng, Đà Nẵng.