Uses of Cenfena

Cenfena has the main ingredient Paracetamol 500mg, belongs to the group of non-steroidal anti-inflammatory drugs, used to reduce fever and relieve mild to moderate pain. Who should the drug be used for and how much?

Cenfena is prescribed by doctors for patients to use in cases such as:
Relief of mild to moderate pain such as: menstrual pain, muscle pain, sore throat, toothache, aches and pains due to cold or flu flu , fever pain after vaccination , headache , migraine , pain after tooth extraction or dental procedures... Cenfena is an effective pain reliever and fever reducer that can replace aspirin however the ingredients are Paracetamol lowers body temperature in febrile patients but is not highly effective in lowering body temperature in normal people.

How to use:
The drug is prepared in the form of film-coated tablets and taken orally. Patients can take the drug with or after meals.
Dosage:
For adults and children over 11 years old: Use 1 tablet/time, cycle every 4 to 6 hours as needed. The maximum dosage should not exceed 8 tablets/day. For children from 4 to 11 years old: Use a dose of 1/2 -1 tablet, once every 4-6 hours. Children under 4 years of age: Should use other formulations more appropriate. Note:
Do not use the drug for pain relief for more than 10 days for adults and more than 5 days for children, unless authorized by the treating doctor. Because severe and persistent pain can be a sign of something more serious that requires a doctor's diagnosis and treatment under supervision.
Do not use the drug for adults and children in case of high fever over 39.5 degrees, fever lasts more than 3 days or has recurrent fever.
Contraindications:
Do not use for people who are hypersensitive to paracetamol. Do not use for patients with glucose 6-phosphate dehydrogenase deficiency. Do not use Cenfena together with other medicines containing paracetamol

The reactions encountered after using an overdose of the drug within 2 hours such as abdominal pain, nausea, vomiting are more serious than causing methemogloin blood (cyanosis of the skin and mucous membranes), impaired liver function leading to yellow skin, consciousness disorders if not handled promptly.
Handling: When the patient knows that he or she has used an overdose of the drug and experiences the above reactions, it is necessary to report it to the doctor immediately to take measures, even if there is no reaction, it should also be reported to the staff. medical.
Usually the doctor will prescribe the use of acetylcysteine ​​​​or methionine as an antidote. Gastric lavage if necessary and preferably within 4 hours after taking the drug. If the overdose is handled too late than 36 hours from the time of taking the drug, it can cause liver damage and difficult to recover.

If at therapeutic doses, Cenfena is well tolerated. The side effects that occur are usually mild, the rate of patients experiencing side effects is very low, some common side effects such as gastrointestinal upset, skin rash and allergic reactions.
In some cases, patients may experience neutropenia, thrombocytopenia and pancytopenia, but compared with aspirin or other non-steroidal analgesics. Paracetamol has the advantage of not irritating the stomach, so the drug is widely used in clinical practice. However, if the patient uses the drug for too long, it can cause kidney toxicity.

People who drink a lot of alcohol and use alcohol with drugs can increase the risk of liver toxicity of Paracetamol.
Long-term administration of the drug in high doses may slightly increase the anticoagulant effect of coumarins and indandion derivatives.
Using together with anticonvulsants such as phenytoin, barbiturates, carbamazepine induces enzymes in the liver microsomes, increases the hepatotoxicity of paracetamol due to increased metabolism of drugs into substances that are toxic to the liver.
Coadministration with anti-tuberculosis drug isoniazid increases the risk of hepatotoxicity, affecting liver function.

Use caution with patients with chronic anemia because it can increase the concentration of methemoglobin in the blood.
People with liver and kidney disease
Alcoholics
The doctor should tell the patient about signs of skin reactions such as Steven-Johnson syndrome (SJS), or Lyell's syndrome, toxic skin necrosis syndrome (SJS). TEN), acute generalized pustular exanthematous syndrome.
Pregnant women: The safety of paracetamol used during pregnancy has not been established, which can affect the development of the fetus. Therefore, the drug should only be used when absolutely necessary and should be consulted by a doctor.
For nursing women: Paracetamol crosses the placental barrier and is excreted in breast milk. However, human studies have not revealed any risk of paracetamol to nursing mothers and breastfed infants. It is necessary to consult a doctor before using the drug.
In short, carefully reading the information about Cenfena before use will help users use the drug safely, effectively and achieve high effects in the treatment of diseases. If you have any further questions, you should contact your doctor for in-depth advice.