Uses of the drug Oliza-10

Drug Oliza 10 mg tablet is indicated in the treatment of schizophrenia & other psychoses with obvious manifestations of positive or negative symptoms.
However, in the following cases, the drug is not allowed to be prescribed to avoid negative effects on the patient's health:
The patient is allergic to the drug's ingredients Narrow angle Glaucoma Women in pregnancy Women female breastfeeding Children under 13 years old. Patients aged 13 -17 years should only use the drug when absolutely necessary and under adult supervision.

2.1. Dosage Depending on the purpose of treating the disease as well as the condition and age of the patient, the doctor will adjust the dose of the drug differently. Specifically:
Dosage for adults:
Schizophrenia: The recommended starting dose is 5 -10 mg/day. Then increase approximately 5 mg/day over 5-7 days to the target dose of 10 mg/day. Maintenance dose: 10 - 20 mg x 1 time / day. Manic episodes: If used as monotherapy, the initial dose is 10 -15 mg/day orally once a day. Maintenance dose is 5 - 20 mg/day. The maximum recommended dose is 20 mg/day. If combination therapy: Initial dose 10-15 mg / day, taken once. Dosage can range from: 5 - 20 mg/day. Prevention of recurrence of bipolar disorder: The dose range is 5 - 20 mg/day. Dosage for special subjects:
Elderly people can use 5 mg/day to start. Patients with renal and/or hepatic impairment: 5 mg/day to initiate. 2.2. Dosage The drug is in the form of capsules and should be taken orally. Patients can take the tablets with or without food, they should be swallowed whole with water and should be taken at the same time each day.

Oliza -10 can cause mild to serious side effects, although before prescribing, your doctor must weigh the benefits and risks of the drug.
Many experts worry that patients may experience suicidal side effects from taking the drug. Because, inherently patients with schizophrenia, bipolar disorder already have extreme psychology leading to a tendency to commit suicide. Therefore, when using Oliza -10, these patients should be closely monitored and avoid overdose. There is also a risk of dementia due to the use of Oliza -10. Patients taking this drug have an increased risk of Parkinson's disease and hallucinations. There have been cases of patients experiencing neuroleptic malignant syndrome when taking olanzapine. Hyperglycemia and diabetes - this is a rare side effect in patients taking Oliza-10. Changes in blood lipids: Olanzapine may cause changes in blood lipids Weight gain : The consequences of weight gain should be considered before initiating treatment. Monitor your weight regularly. Anticholinergic activity: Caution should be exercised when administering the drug to patients with prostatic hypertrophy, narrow-angle glaucoma or paralytic ileus and related conditions due to its anticholinergic effects. In addition, patients may experience other undesirable side effects such as: leukopenia, thrombosis, convulsions, tardive dyskinesia, postural hypotension, hyperthermia...

Drug interactions can reduce the effect of Oliza -10 tablet, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including over-the-counter medicines, vitamins, prescription drugs, and herbal products. Do not start, stop or change the dose of any medicine without your doctor's consent.
Here are some drugs that can interact with Oliza -10:
The olanzapine component in the drug, when combined with levomethadyl, increases the risk of cardiotoxicity with metoclopramide due to an increased risk of extrapyramidal syndrome, neuroleptic malignant syndrome. Co-administration of Oliza -10 with Diazepam increases the risk of orthostatic hypotension. Combining Oliza -10 with inducers of CYP1A2 (carbamazepine, phenobarbital, phenytoin, rifampicin, omeprazol) decreased olanzapine concentrations. Activated charcoal reduces the bioavailability of orally administered olanzapine by approximately 50-60% and should be administered at least 2 hours before or after olanzapine administration. Warfarin, Antacids (aluminum, magnesium) or cimetidine did not significantly affect the pharmacokinetics of olanzapine. Olanzapine may antagonize the effects of levodopa and dopamine agonists. Olanzapine enhances the effects (constipation, dry mouth, sedation, urinary retention, visual disturbances) of anticholinergics, potentiating the hypotensive effect of antihypertensives. Oliza -10 contains the active ingredient Olanzapine. It is an important ingredient prescribed and indicated for the maintenance treatment of schizophrenia, as well as other psychotic illnesses.