Indications of Varogel 10ml

Table of content

Varogel is formulated as an oral suspension indicated for the treatment of gastric and duodenal ulcers, symptoms of increased gastric acid secretion, gastric irritation syndrome, and gastroesophageal reflux disease (GERD).

1. What is Varogel 10ml?

Varogel 10ml is formulated as an oral suspension. The medication is indicated to alleviate the discomfort associated with gastric pathologies. Each package contains 10ml and is packaged as one box containing 20 sachets.

2. Composition of the medication

Active ingredients:

  • Aluminum hydroxide gel: ~ 0.4 g aluminum oxide;  
  • Magnesium hydroxide 30% paste: ~ 0.8004 g Mg(OH)2;  
  • Simethicone 30% emulsion: ~ 0.08 g Simethicone.  

Excipients:

  • 70% D-Sorbitol solution;  
  • Xanthan gum, xylitol;  
  • Licorice extract;  
  • Povidone K30;  
  • Avicel 59T;  
  • Stevion 100S;  
  • Chlorhexidine acetate;  
  • Malt flavor, peppermint flavor, ethanol;  
  • Purified water.

3. What are the effects of Varogel 10ml?  

Varogel is indicated for the treatment of the following conditions:

  • Treatment of acute and chronic gastric and duodenal ulcers.  
  • Management of symptoms such as heartburn and acid regurgitation due to increased gastric acid secretion and gastric irritation syndrome;  
  • Treatment of gastroesophageal reflux disease (GERD).  

However, Varogel should not be used in the following cases:

  • Hypersensitivity to any component of Varogel;  
  • Severe renal impairment;  
  • Patients exhibiting signs of hypophosphatemia;  
  • Patients with hypermagnesemia;  
  • Varogel is contraindicated in children.

4. Dosage and administration of Varogel for effective use

Administration of Varogel:

  • Varogel is formulated as a gel for oral intake.  
  • It is recommended to take Varogel between meals or 30 minutes to 2 hours after meals, in the evening before bedtime, or when symptoms arise.  

Dosage of Varogel for adults:

  • The usual dosage of Varogel for the treatment of acute and chronic gastric and duodenal ulcers is: Take 10ml (1 sachet) at a time, 2–4 times daily.  
  • The typical dosage for managing symptoms of increased gastric acid secretion and gastric irritation syndrome, as well as GERD, is: Take 10ml (1 sachet) at a time, 2–4 times daily.  
  • Research regarding the dosage of Varogel for children has not been conducted. Therefore, it is best to consult a physician for additional details.

5. Side effects of Varogel  

Some side effects that may occur when using Varogel 10ml include:

  • Astringent taste, abdominal distension, hard and white stools;  
  • Side effects such as nausea and vomiting;  
  • Hypophosphatemia may occur with prolonged or high-dose administration;  
  • Aluminum toxicity, osteomalacia may occur in patients with high blood urea syndrome;  
  • Dementia, microcytic anemia.

6. Management of overdose or missed doses  

Symptoms of Varogel overdose include nausea, vomiting, gastrointestinal irritation, diarrhea, or constipation. Management of overdose should be symptomatic and supportive. Therefore, it is essential to transport the patient to a healthcare facility upon noticing signs of overdose.  

If a dose of Varogel is missed, it should be taken as soon as possible when remembered. However, if it is close to the next scheduled dose, the missed dose should be skipped, and the next dose should be taken at the scheduled time. Doubling the prescribed dose is not recommended.

7. Interactions with Varogel  

When using Varogel, the concentrations of the following medications may be reduced:

  • Tetracycline;  
  • Digoxin;  
  • Indomethacin;  
  • Iron salts;  
  • Isoniazid;  
  • Allopurinol;  
  • Benzodiazepines;  
  • Corticosteroids;  
  • Penicillamine;  
  • Phenothiazines;  
  • Ranitidine;  
  • Ketoconazole;  
  • Itraconazole.  

Additionally, if you are currently taking any medications, vitamins, or dietary supplements, it is essential to inform your physician before using Varogel.

8. Considerations for Using Varogel 10ml  

  • Use Varogel in accordance with the prescribed dosage and administration guidelines;  
  • If symptoms do not improve after two weeks, consult a healthcare professional (physician/pharmacist);
  • Regarding dosage, do not exceed Varogel ≥ 6 packets per day without a physician's directive;  
  • Exercise caution when using Varogel in individuals with congestive heart failure, renal insufficiency, edema, liver cirrhosis, those on a low-sodium diet, and individuals who have recently experienced gastrointestinal bleeding;  
  • Elderly patients may experience constipation and hardened stools while using the medication;  
  • Regular monitoring of phosphate levels is recommended during prolonged treatment with Varogel;  
  • Varogel does not affect the central nervous system in terms of symptoms such as headache and dizziness; therefore, the use of Varogel will not impair the ability to operate vehicles and machinery;  
  • For pregnant and lactating women: Antacids in general are considered safe if not used long-term and at high doses. However, there have been reports of side effects such as elevated or decreased serum magnesium levels, and increased deep tendon reflexes in the fetus and infants. Caution is advised when using Varogel in pregnant women;  
  • Lactating women: The medication is excreted in breast milk but not in sufficient amounts to cause adverse effects in breastfeeding infants. Therefore, to ensure the safety of the child, it is advisable to exercise caution when using Varogel.  

Storage Instructions for Varogel:  

  • Keep Varogel out of reach of children and household pets.  
  • Store Varogel in a cool, dry, and well-ventilated area. Avoid direct sunlight exposure or placing the medication in damp locations.  
  • The optimal storage temperature is < 30°C.  

The above information includes the indications, dosage, and administration of Varogel. It is essential to read the instructions carefully and consult a physician/pharmacist before use. Self-medication without professional guidance is strongly discouraged due to the potential for unforeseen adverse effects.

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